Multi-omics: An integrative approach to biomedical research

With the improving sequencing landscape, it is safe to say we are on the cusp of an omics revolution. As a result, we are experiencing an increased interest in multi-omics studies – the study of more than one molecular layer in a system in tandem.

We already take advantage of multi-omics studies to aid in our understanding of how perturbations in the molecular layers influence other molecules in the system. However, the main challenge is making this type of study more accessible routinely and how we apply the findings in practice. This report covers the motivations behind embarking on such studies, highlights some of the recent success stories, and discusses methods of approaching analysis.

Readers of this report will gain:

  • First-hand experiences of embarking on multi-omics analyses
  • Exclusive interviews with researchers' helpful tips
  • Case studies about how multi-omics analysis has been used
  • Insights into what the future may hold for multi-omics analysis

Report contributors include:

  • Omer Bayraktar, Appointed Cellular Genetics Group Leader, Wellcome Sanger Institute
  • Tamas Korcsmaros, Group Leader, Earlham Institute
  • Rob Ewing, Professor, University of Southampton
  • Esperanza Anguiano, Scientific Associate Director, Clinical Genetics and Genomics, Bristol-Myers Squibb
  • Bin Chen, Assistant Professor, Michigan State University College of Human Medicine
  • Evan Newell, Associate Professor, Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center
  • Peter Sorger, Otto Krayer Professor of Systems Biology, Harvard Medical School

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